Isopentenyl pyrophosphate

Isopentenyl pyrophosphate
Identifiers
CAS number 358-71-4 Y
PubChem 15983957
ChemSpider 13115335 Y
MeSH isopentenyl+pyrophosphate
ChEBI CHEBI:128769 Y
Jmol-3D images Image 1
Properties
Molecular formula C5H12O7P2
Molar mass 246.092
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Isopentenyl pyrophosphate (IPP) is an intermediate in the classical, HMG-CoA reductase pathway used by organisms in the biosynthesis of terpenes and terpenoids. IPP is formed from acetyl-CoA via mevalonic acid. IPP can then be isomerized to dimethylallyl pyrophosphate by the enzyme isopentenyl pyrophosphate isomerase.

IPP can be synthesized via the alternative, non-mevalonate pathway of isoprenoid biosynthesis instead, where it is formed from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP) by the enzyme HMB-PP reductase (LytB, IspH). The non-mevalonate pathway is utilized by many bacteria, apicomplexan protozoa such as malaria parasites, and the plastids of higher plants.

See also

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